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doi: 10.1111/j.1524-4725.2005.31725

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In tumors carrying TP53 mutations, the HCC-specific hotspot mutations R249S and R249M, the normal apoptotic response to oxidative stress may be compromised [304, 305]

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As a result, plant cells respond defensively to oxidative damage by removing ROS and maintaining antioxidant defense compounds at levels that reflect ambient environmental conditions

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