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Taurine attenuates activation of hepatic stellate cells by inhibiting autophagy and inducing ferroptosis

Purves-Tyson et al., 2017

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The identified lipids spanned five major categories: fatty acyls, glycerolipids (GLs), glycerophospholipids (GPLs), sphingolipids (SPLs), and sterol lipids (STLs)

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Excessive reactive oxygen species (ROS) disrupt cellular redox homeostasis and directly induce oxidative modifications (e.g., carbonylation, disulfide bond disruption) in tight junction proteins, compromising gastrointestinal barrier integrity and increasing intestinal permeability