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Furthermore, single-cell multiomic and barcode-based lineage tracing analyses have shown that even transcriptomically and epigenomically homogeneous starting hESC-derived DA progenitors can give rise to heterogeneous grafts after terminal differentiation in vivo in PD models (Tiklov et al., 2020

Increases production and activity of white blood cells and antibodies

J Endocrinol Invest 36(6):444449

A review by Hewlings et al

To get insight into the biological roles of CDDs, it is important to comprehend the nature and mechanisms of their formation which often proceeds via interactions of DNA with endogenous reactive metabolites and various exogenous factors