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This work was funded in part by the Division of Intramural Research of the National Institute of Environmental Health Sciences

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Notably, this reduced AUC SER contrasts with the increased AUC GLUC observed in a classical glucose tolerance test in diabetics, demonstrating the striking dysregulation of l-serine homeostasis in diabetic mouse models

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In this review, we summarize the current knowledge on the pathogenesis of diabetic neuropathy, especially how metabolic factors affect the course of the disease and the indispensable role of the inflammatory response

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