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Pretreatment of PC12 cells with low-dose bovine serum albumin (BSA) under OGD conditions enhanced the level of GSH and activity of SOD and thereby reduced the cytotoxicity induced by OGD (119)

United States Patent 5,164,367, November 1992.

NAC (N-AcetylCysteine) is a precursor to the important antioxidant glutathione and relieves the symptoms of chronic bronchitis.*

They are phagocytosed by macrophages as foreign particles and recognized by Toll-like receptors 2 and 4 (TLR2/TLR4), which subsequently activate and oligomerize the NLRP3 complex

Due to a massive cytokine release, this clinical condition is considered as a cytokine storm syndrome

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