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Plasma-derived exosomes were characterized, their uptake by PBMCs was visualized and consequent ROS generation was assessed in in-vitro co-culture

NAC, a sulfur-containing derivative of the amino acid L-cysteine, supports antioxidant and detoxification mechanisms in the body

This is the first demonstration that Cited2 functions as a Smad3/p300-interacting transcriptional co-activator in modulating the expression of MMP9, which could affect tumor cell invasion mediated by TGF-.

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