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In general, the lack of harmonization between the different countries, the need for careful characterization, reliable in vitro release techniques and biologically relevant testing make regulatory requirements and the approval pathways for liposomes challenging [154,155]

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Keywords: intervertebral disc degeneration, 3D bioprinting, hydrogel, novel therapy, challenges Introduction Lower back pain is a prevalent condition that impacts approximately 80% of the global population

About this article Cite this article Douzi, W., Hohenauer, E., Dupuy, O

Children between 6 months and 59 months of age Pregnant women All adults aged 50 years and older Pregnant women or women planning pregnancy Adults and children with chronic medical conditions People with chronic health conditions (e.g., lung, cardiovascular, renal, hepatic, or neurological disorders