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In addition, magnesium is involved in the regulation of various nerve receptors, such as NMDA and 5-HT3, which are involved in the development of neuropathic pain experienced by FM patients

These receptors regulate the transcription of genes involved in lipogenesis, fatty acid oxidation, and cholesterol transport

doi: 10.1007/s00256-008-0562-0

Indeed, human saphenous vein endothelial cells incubated with high levels of endothelin-1 displayed decreased NO production and increased PKC and translocation

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ALC activated ERK signaling, increased histone acetylation, promoted PPAR nuclear translocation, and selectively enhanced mitochondrial respiration in mature OLs