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J.et al (2004)

Laboratory studies have also shown that it can reduce the body's response to acute stress, as it significantly affects the levels of substance P, beta-endorphin and cortisol in the hypothalamus and blood plasma

NAC has direct antioxidant activity but also increases intracellular levels of cysteine which facilitates GSH synthesis [45]

Ann Rheum Dis (2023) 110

The pyroptosis-related proteins NLRP3, caspase-1, and IL-1 have been observed to be up-regulated in the pentylenetetrazole (PTZ) kindling model, amygdala kindling model, PILO model, as well as in the hippocampus of temporal lobe epilepsy patients [10, 11, 50, 51]

Tissue repair and remodeling models