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As an exposure-based control, cells passaged for five days but not previously exposed to Zn were also tested

Finally, we show in mice that a ketogenic diet and the delivery of BHB as a ketone ester drink restores CD4 + T cell metabolism and function in severe respiratory infections, ultimately reducing the mortality of mice infected with SARS-CoV-2

2020;30:43994417.e4397

Individual bar plots highlight that compared to nave controls, classic inflammatory lipid mediators (arachidonic acid [AA], 5-hydroxyeicosatetraenoic acid [5-HETE], 12-HETE, 11,12-dihydroxyeicosatreinoic acid [11,12-DiHETrE]) were elevated in individuals with prior COVID-19, whereas the levels of lipid mediators with anti-inflammatory properties (arachidonoyl ethanolamide [AEA], docosahexaenoyl ethanolamide [DHEA]) were decreased (Supplemental Figure 2)

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