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2.2 Neuroinflammation in the brain and cognitive dysfunction in diabetes Neuroinflammation itself is a defence mechanism against acute the CNS damage and ameliorates the effects of toxic substances produced in brain nerve cells, but persistent neuroinflammation inhibits nerve regeneration, leading to neurodegeneration making the patient cognitively impaired

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The Multidrug Resistance Protein MRP1 Mediates the Release of Glutathione Disulfide From Rat Astrocytes During Oxidative Stress. Journal of Neurochemistry 76: 627636

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