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For NMR measurements, the samples were re-suspended in 200 L NMR buffer (50 mM sodium phosphate buffer in D 2 O at pH 7.2 with 0.1 mM DSS (4,4-dimethyl-4-silapentane-1-sulfonic acid) for referencing)

2010;17(Suppl 1):S2

A Phase II study (NCT04515394) also evaluated the preliminary antitumor activity of tepotinib in combination with cetuximab in patients with RAS/BRAF WT mCRC having acquired resistance to anti-EGFR due to MET amplification

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BA also regulates the cholesterol metabolic pathway, allowing cholesterol to be eliminated as a water-soluble product and impaired regulation can lead to an inflammatory response that can exacerbate the development of MASLD (79)

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