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10.1523/jneurosci.3597-04.2004 74 MarottaD

Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

Minor GI discomfort when starting oral dosing, usually limited to the first 2 to 3 days

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The frequency of administration may decrease over time as well once the vitamin has been able to build up a bit in the body

[111] targeted N-to-B delivery of thyrotropin-releasing hormone (TRH)(a polypeptide used for treating suicidal patients), using fast degrading poly(sebacic anhydride) (PSA) NPs