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The role of macrophages in the resolution of inflammation

Symptom-focused strategies avoid triggers but don't address why cellular processing systems became overwhelmed initially
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C.VialsF.et al

10.1016/j.tiv.2009.04.007 261 ZhangQ.ZhaoX

However, hepatocytes do not strictly depend from ME-1 activity for NADPH synthesis: in ME-1 deficient mice, after an initial depletion, the GSH levels recover quickly and sensitivity to acetaminophen-induced liver injury was unaltered [26]
