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Effects of extended-release 7-nitroindazole gel formulation treatment on the behavior of Shank3 mouse model of autism

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Interestingly, a few cases of differential metabolic changes (ie, fold change of MTX treatment over basal levels) were associated with MTX resistance (at 96 hours)

doi: 10.1111/j.1440-1819.2012.02392.x

In loss-of-function experiments, Itgb1 i Esm1 KO embryos ( Itgb1 lox/lox Esm1-CreERT2 tg/+ ) were compared to Itgb1 i Esm1 HET ( Itgb1 lox/+ Esm1-CreERT2 tg/+ ) or control littermates ( Itgb1 +/+

however, antioxidants serve as a critical mechanism to reduce such damage