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The combined treatment demonstrated significantly greater efficacy than standard-dose pregabalin or acetyl-l-carnitine alone, in terms of both pain symptoms measured by improvement on the VAS score (+12.8%) and neurosensory symptoms measured by the DN4 tool (+22%)

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Histological changes are similar to those observed in the Reye's syndrome, with early production of microvesicular steatosis followed by development of centri-lobular necrosis [23]

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Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care

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L-carnitine has grown in popularity as a dietary supplement due to its potential advantages for a variety of aspects of human health, athletic performance, and recuperation

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However, following overdose the half-life may be prolonged to as long as 30 hours [11,16,17]

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Carnitine as an essential nutrient

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