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Present in KLOW at 10mg, it is researched for actin sequestration, endothelial cell migration, angiogenesis support, and anti-inflammatory modulation in preclinical models
At the level of gene transcription, the fact that three different proteins can be synthesized from gpx4, due to the presence of multiple transcriptional start sites, yielding the mitochondrial (m-), nuclear (n-), and cytosolic (c-) GPx4 forms, makes the issue of gene regulation extremely complex 54
