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doi: 10.22038/IJBMS.2017.24801.6167 206 YingYL

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Preclinical research demonstrates that small molecules or stabilized peptide fragments may be absorbed through these tissues, though variability in saliva, pH, and mucosal permeability affects systemic exposure

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Disadvantages of antimicrobial peptides as therapeutic drugs in general i , Antimicrobial peptides generally are susceptible to proteolytic degradation