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Ipamorelin is made up of five amino acids forming a pentapeptide, and works as a selective agonist targeting the ghrelin or growth hormone secretagogue receptor (GHS-R)

This is due to increased oxidative stress, which accelerates aging

[10] Additionally, the authors concluded that the severity of autoimmune thyroid disease (AITD) did not correlate with whether one had this gene variation or not

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527 Mitophagy regulator Activation of mitophagy promotes the removal of damaged mitochondria and avoids excessive ROS production, as well as the corresponding oxidative stress and inflammation

These results appear to contradict finding reported in vivo (Payabvash et al., 2006)