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The mixture was injected intraperitoneally

At this concentration, 0.1mL (10 units) contains 500mcg total peptide (250mcg each), and a 200mcg + 200mcg dose requires 0.08mL (8 units) easily measurable on standard U-100 syringes without fractional unit guesswork

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In instances where an increase in estrogen is expected, such as in testosterone replacement therapy, estrogen blockers may be used in conjunction with testosterone to prevent the development or progression of gynecomastia

Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins)