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(2024) 10:e32470

Following this, vitamin B 12 serves as a co-enzyme for methionine synthase, the essential enzyme facilitating the transfer of a methyl group from 5-methyl-tetrahydrofolate to Hcy, thereby promoting the regeneration of Met (Preynat et al., 2009)

doi: 10.1016/j.jconrel.2016.01.028, PMID: [DOI] [PubMed] [Google Scholar] 140.Kisakova LA, Apartsin EK, Nizolenko LF, Karpenko LI

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Clinically, a higher dose is required to obtain the original response

Although NAC is promising as a supplement to both boost glutathione levels and potentially mitigate some of the issues related to oxidative stress [57,58], the research is not conclusive [59,60,61,62], and some of the findings are disease specific