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In addition to the production of various inflammatory neurotoxic mediators, microglia secretes the proteolytic lipolytic enzymes which ultimately lead to the destruction of myelin [23]

A range of cellular factors such as osteopontin, GAS6, TGF-, and BMP contribute to DTC dormancy by affecting cellular behavior and interactions [37,38,39,40]

While manufacturers state its acceptable for unopened vials, we recommend refrigerating them upon arrival

The researchers found that implementing antimicrobial stewardship when caring for people with CF provides benefit in this complex patient population

Exosomes exhibit intrinsic biocompatibility and have demonstrated enhanced efficiency in CNS drug delivery, enabling targeted release of neuroprotective agents with reduced systemic toxicity (96)

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