nadp nadph glutathione Total + /NADPH (A), total (GSH + GSSG) (B), and Higher plant NADP+-dependent isocitrate dehydrogenases,

When a global AN(C)OVA F-test revealed a significant overall result, Tukeys HSD for all pairwise comparisons or Dunnetts test for multiple-to-one comparisons was used as a post hoc test

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Add to this the fact that some depigmenting ingredients affect not only dark spots but also the skin around them, and it becomes clear that it's not always easy to find the best dark spot serums to minimize dark spots and hyperpigmentation on dark skin

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