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However, existing evidence directly connecting anthocyanin antioxidant activity to stage-specific alterations in oxidative stress in GDM is insufficient, emphasizing a need for additional research to explore whether targeted anthocyanin interventions could more effectively modulate oxidative stress at various stages of GDM

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Thus, chemoprevention by oltipraz was greatly diminished in Nrf2 -knockout mice (4,63), and many similar studies in Nrf2 -knockout mice have been carried out with agents that protect against skin carcinogenesis induced by ultraviolet light or chemicals (18,19,64)