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Similarly, lysosome associated protein transmembrane 4B (LAPTM4B) blocks ferroptosis by suppressing NEDD4L/ZRANB1-mediated ubiquitination and degradation of SLC7A11 (31)
The onset of systemic inflammation may allow inflammatory mediators to cross over the BBB and impact microglia, further exacerbating neuroinflammation
Murtaza M, Dawson SJ, Tsui DW, Gale D, Forshew T, Piskorz AM et al
Several common HLA-DR types share largely overlapping peptide binding repertoires
In some circumstances, recovery is possible even after prolonged resuscitation
