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A B12 deficiency can lead to a weakened immune system

Test compounds were screened in biochemical assays for activity against three structurally similar methyltransferases, including catechol-O-methyltransferase (COMT), DNA (cytosine-5)-methyltransferase 1 (DNMT1), and protein arginine methyltransferase 3 (PRMT3)

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This is an autoimmune condition where the stomach fails to produce intrinsic factor (IF), the protein required to absorb B12 naturally

If there is a deficiency of Vitamin B12, then it could lead to the accumulation of a compound called homocysteine

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