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Although used less frequently than NAC, cysteine precursor in the form of prodrug, 2-oxothiazolidine-4-carboxylate (OTC), is also used to enhance cellular GSH level [247]

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The importance of OxPhos is further highlighted by the fact that a cytarabine-resistant population of AML cells show enrichment not in LSCs per se , but in cells with up-regulated mitochondrial mass, membrane potential, and OxPhos

Most clinical research that looks at long-term outcomes typically follows participants for three to six months

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