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Pharmacokinetic studies of several bioactive compounds have demonstrated limited oral bioavailability, rapid metabolism, extensive first-pass hepatic clearance, and low systemic exposure

(4) the intracavitary, subcutaneous, intramuscular administration, and (5) the ozone insufflation via rectum is the most unreliable administration route because we never know the percentage of the really effective ozone dose insufflated into the rectum

Murillo AG, Hu S, Fernandez ML

In a healthy body, L-carnitine's primary job is logistical

10.1016/j.envint.2019.05.083 124 LaiJ

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