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Biological activity assays revealed that MSNs-ss-SA exhibited superior efficacy in inducing resistance to rice sheath blight compared to conventional SA, which was primarily due to its ability to enhance physical barrier formation, strengthen antioxidant defense systems, upregulate the expression of key defense-related genes, and increase chitinase synthesis, collectively triggering both systemic acquired resistance and induced systemic resistance

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Although several studies now recognize these reprogrammed activities as hallmarks of cancer, it remains unclear which are the pathways involved in regulating metabolic plasticity