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In summary, metabolic heterogeneity in CRC is not merely a passive adaptive feature but actively shapes differential treatment responses

more than 25% of collagen fibers of a diffuse structure with a loss of boundary between individual fibers (score 3)

The gut microbiome often referred to as a second brain or even an organ in itself is a vast community of microorganisms living in your digestive tract

It may support healthy skin by reducing inflammation and oxidative stress and also improve energy metabolism

J Am Soc Nephrol 33:11051119 Cai TT, Ye XL, Li RR, Chen H, Wang YY, Yong HJ, Pan ML, Lu W, Tang Y, Miao H et al (2020) Resveratrol modulates the gut microbiota and inflammation to protect against diabetic nephropathy in mice

Overall, berberine has an outstanding safety profile