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Lets deal with the simpler one firstthe presence of cysteine

Tomioka, N

During hypoxia, oxygen sensing and signal transduction are largely governed by prolyl hydroxylase domain proteins (PHD1/2/3), which hydroxylate target proteins in an oxygen-dependent manner 8,9

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This principle applies to both direct injections and a whitening drip, since both delivery methods work through the bloodstream at a comparable pace

J Mol Endocrinol (2012) 48:193202