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(b) N-terminal part of GRXS14 protein alignment (Jalview) showing the presence or absence of N-terminal extensions indicative of putative N-terminal targeting peptides

The imbalance between the production of reactive oxygen species (ROS) and the availability of antioxidants or free radical scavengers can cause oxidative stress, and that further activates an abundance of transcription factors and pro-inflammatory genes such as NF-B, p53, HIF-1, PPAR-, -catenin/Wnt, and Nrf2 [5,6,7]

Identification of SLC22A5 Gene Mutation in a Family with Carnitine Uptake Defect