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Using 2D-DIGE analysis of bull sperm, it was shown that ALB, TIMP, spermadhesin-1, and binder of sperm proteins (BSP)-1, 3, and 5, PEBP1, and AKI in sperm and seminal plasma were more abundant in sperm from high fertility bulls, while PSMA6, ELSPbP1, CCT5, CCT8, and CLU were in greater amounts in seminal plasma and in sperm from low-fertility bulls

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Therefore, in addition to GSSG accumulation, a decrease in Grx expression/activity may also lead to increased protein S -glutathionylation
