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To address these transformation challenges, it is recommended to conduct a comprehensive evaluation of fibroids using imaging modalities such as ultrasound or MRI prior to ER and PR testing

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J Clin Oncol 8(7):12771280 Wen PY, Macdonald DR, Reardon DA, Cloughesy TF, Sorensen AG, Galanis E, Degroot J, Wick W, Gilbert MR, Lassman AB, Tsien C, Mikkelsen T, Wong ET, Chamberlain MC, Stupp R, Lamborn KR, Vogelbaum MA, van den Bent MJ, Chang SM (2010) Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group

4.4 Heat exposure Heat is typically used to improve heat tolerance, although it has also been shown to improve physical performance (Waldron et al., 2021)