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One study shows levels increase by 40% in whole blood, 25% in red blood cells, and 28% in plasma with just two weeks of supplementation

In summary, the implication of IGF-1 in glucose and lipid metabolism and its derangements when the GH/insulin/IGF-1 axis balance fails is well documented

Indeed, two preclinical studies have suggested a putative role for M6G in potentiating opioid withdrawal symptoms [128, 243]

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