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doi: 10.1258/acb.2011.011039

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Hyperhomocysteinemia Higher homocysteine levels are associated with a phenomenon called "methionine loading." A deficiency of Vitamin B12 along with B6 and folate usually prevents the conversion of homocysteine to methionine, increasing the levels of homocysteine

Other risk factors include certain gastrointestinal conditions, autoimmune conditions such as pernicious anaemia, long-term use of some medications, and increasing age

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Human or veterinary use is prohibited under this research-use designation.The research-use-only designation means that scientists and institutions purchasing these compounds understand the legal and regulatory framework surrounding their use