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Additionally, NSW affects methylation of immune-modulatory genes and human endogenous retroviral elements such as ERVFRD-1, HERV-L, and HERV-P, indicating combined effects of circadian and metabolic stressors on immune epigenetic regulation 234

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Studies on cultured dermal papilla cells, which are critical for regulating the hair growth cycle, investigate the peptide's influence on cell proliferation and the expression of growth factors like VEGF

Preclinical studies suggest selective cytotoxicity toward cancer cells expressing abnormal p53/HDM2 while sparing normal cells [2] [6]

Beyond AN, there are other factors linked with OSF pathogenesis

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