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61 NiuY.DesMaraisT

Suppression of abdominal fat and anti-hyperlipidemic potential of Emblica officinalis: Upregulation of PPARs and identification of active moiety

Declining IgG levels suggest successful immunosuppression, while persistently high levels may indicate sub-optimal therapy or ongoing inflammation, necessitating treatment adjustments [50]

98 NagyE.EatonJ

In contrast, several studies suggested that the activation of ERK and JNK phosphorylates MITF at Ser 73 , which leads to its ubiquitination and degradation, thus subsequently down-regulating melanogenesis (not shown in Figure 3) [26,3941]

doi: 10.1016/j.cbi.2010.12.002