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A Mediterranean-style plan rich in fish, nuts, olive oil, legumes, and whole grains promotes healthy inflammation levels and supplies micronutrients required for spermatogenesis

Neurological function depends heavily on adequate methylcobalamin for myelin sheath maintenance and neurotransmitter synthesis

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Supplementation of B12 for a number of weeks prior to supplementing methylfolate, will avoid reactions to methylfolate

doi:10.1016/j.clinbiochem.2003.08.004