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Absorption of methionine sources in animals-is there more to know

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Negrao MV, Skoulidis F, Montesion M, Schulze K, Bara I, Shen V, Xu H, Hu S, Sui D, Elamin YY, Le X, Goldberg ME, Murugesan K, Wu CJ, Zhang J, Barreto DS, Robichaux JP, Reuben A, Cascone T, Gay CM, Mitchell KG, Hong L, Rinsurongkawong W, Roth JA, Swisher SG , Lee J, Tsao A, Papadimitrakopoulou V, Gibbons DL, Glisson BS, Singal G, Miller VA, Alexander B, Frampton G, Albacker LA, Shames D, Zhang J, Heymach JV

Later research conducted by the same group showed, however, a robust reduction in most immune cell populations in the CNS of GFAP-IB-dn mice at chronic EAE phase compared with controls (62)

The stimulated astrocytic GSH export induced by these compounds is prevented by inhibition of Mrp1, demonstrating that this transporter mediates the druginduced stimulated GSH export, while the basal GSH export is only inhibited by around 60% in the presence of the Mrp1 inhibitor MK571 (Hirrlinger et al

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