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In intranasal delivery targeting the olfactory mucosa, overcoming the mucus barrier is the first challenge: drugs must dissolve in or traverse the mucus layer before encountering enzymatic degradation or mucociliary clearance (Rassu et al., 2018)
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doi: 10.1007/s10753-024-02025-2 96 GaoXWangCShenXTLiCYLiYCGaoHet al
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If youre combining treatments (like CRYO Facials or Red Light Therapy), allow 7590 minutes total
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