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In the multivariate analysis, l-carnitine administration (OR 3.51, 95% CI 1.239.99, p = 0.019) and baseline NIRS data of 0.07 mMmm (OR 5.21, 95% CI 1.6916.0, p = 0.0041) were found as significant independent factors (Table 3)

Numerous lines of evidence from animal and human investigations have shown that when there are pathological disorders linked with muscle wasting such cancer and Chronic Obstructive Pulmonary Disease (COPD), apoptosis (myonuclear apoptosis) is elevated (Pirestani et al., 2011)

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10.1093/gerona/glaa248 40 GongJ.ZhaoH.LiuT.LiL.ChengE.ZhiS.et al (2019)