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9a, and Supplementary Fig

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5a, diamide exposure markedly increased intracellular protein-GSSG adduct formation

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Because glutathione synthesis depends on adequate cysteine availability, NAC supplementation has become one of the most widely researched strategies for supporting healthy glutathione levels

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Our synthesis revealed that mycotoxin decontamination, control, and detoxification strategies cut across pre-and post-harvest preventive measures

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Recent studies in seven CF patients treated with 600 mg of a GSH aerosol administered twice daily for 3 d showed an increase in ELF GSH levels and should provide a platform for future clinical trials [93]

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Unresolved questions It remains to be established whether CNS symptoms reported in some patients with gamma-glutamylcysteine synthetase are related to the enzyme defect or not

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