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9a, and Supplementary Fig

5a, diamide exposure markedly increased intracellular protein-GSSG adduct formation

Because glutathione synthesis depends on adequate cysteine availability, NAC supplementation has become one of the most widely researched strategies for supporting healthy glutathione levels

Our synthesis revealed that mycotoxin decontamination, control, and detoxification strategies cut across pre-and post-harvest preventive measures

Recent studies in seven CF patients treated with 600 mg of a GSH aerosol administered twice daily for 3 d showed an increase in ELF GSH levels and should provide a platform for future clinical trials [93]

Unresolved questions It remains to be established whether CNS symptoms reported in some patients with gamma-glutamylcysteine synthetase are related to the enzyme defect or not
