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The G1 biotype had higher polygenic risk scores and higher DNA methylation [35]

Liang, R., Robb, F

This suggested that analogous proteins (later discovered as -arrestins 1 and 2) could desensitize the 2 AR physiologically

Diverse Compounds From Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis
This might be due to the abundance of repetitive/transposable elements (TEs) in their genomes, despite having genome sizes of only about 500 Mb (Jaillon et al., 2007
