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The meta-analysis data on L-carnitine showed an average weight reduction of 1.21 to 1.33 kg compared to placebo groups, according to studies published in Clinical Nutrition ESPEN and Obesity Reviews

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Orphanet J

The schedule mirrors the clinical-trial protocols that drove substantial weight loss around 20% of body weight over 72 weeks on the 15 mg dose [2] while holding gastrointestinal effects down through gradual escalation [1] [4]