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Since our screen utilized FAT-7 expression, we tested whether the nuclear hormone receptor NHR-49, which regulates FAT-7 and lifespan (Naim et al, 2021

For dual-luciferase reporter assays, 100 L protoplasts were used for each transfection experiment

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Within a single tumor, different cell states co-exist: highly differentiated, proliferative melanocytic cells, which are associated with high MITF levels, whereas slow-cycling, dedifferentiated, invasive stem-like cells correlate with low MITF levels (Arozarena and Wellbrock, 2019

2013;4(4):e00460-13