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Low levels of B12 can disrupt neurotransmitter balance, potentially leading to increased anxiety and depressive symptoms

EPSM horses have a genetic mutation in an enzyme, glycogen synthase 1, which causes this enzyme to be more active than normal

Moreover, given the evidence, which we previously summarized from human and experimental studies, that PD is a prion disorder originating in the gut [3], the ability of UA to modulate intestinal integrity and colonic immune milieu [10,38] may be considered for early dietary intervention to mitigate PD pathogenesis [91]

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10.1016/j.cofs.2023.101048 [DOI] [Google Scholar] Dank, A