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Fda approval summary: tocilizumab for treatment of chimeric antigen receptor T cell-induced severe or life-threatening cytokine release syndrome

Necropsy confirmed splenomegaly and lymph node enlargement (Fig

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Keywords: ulcerative colitis, GHK-Cu, SIRT1/STAT3 pathway, co-culture system, network pharmacology, molecular docking 1 Introduction Ulcerative colitis (UC) is a chronic, relapsing form of inflammatory bowel disease (IBD) characterized by immune system dysfunction and pathological overactivation of mucosal immune responses, leading to persistent inflammation and subsequent colonic mucosal injury (Raine et al., 2022)

LIF, leukemia inhibitory factor

This reagent is a prosubstrate that releases luciferin when it is cleaved by activated caspase-3/7