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MASH/NAFLD: Given the liver fat-reducing effects of GLP-1 receptor agonism, orforglipron may be evaluated for metabolic dysfunction-associated steatohepatitis (MASH), a condition affecting an estimated 5-6% of the adult population for which effective oral therapies are urgently needed
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The skin is pinched to create a fold, and the needle is inserted into the fold at an angle
Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg has shown promising results in early-phase trials
It does mean you should discuss the symptom with a healthcare provider, who can assess how severe the nausea is and suggest ways to manage it
