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By virtue of inducing broad cell growth, growth hormone related peptides (CJC-1295, Ipamorelin, and Tesamorelin), carry the potential risk of cancer

Willard ., " GIP GLP-1", JCI Insight, 5, 17,

The molecular basis of memantine action in Alzheimers disease and other neurologic disorders: low-affinity, uncompetitive antagonism

Importantly, even the integrity of BBB can vary among PD patients, altering permeability of therapeutic agents and further complicating the development of effective PLGA nanoparticle therapies 145,146

Swaminathan M, Kantarjian H, Daver N, Borthakur G, Ohanian M, Kadia T, DiNardo C, Jain N, Estrov Z, Ferrajoli A, Garcia-Manero G, Konopleva M, Andreeff M , Pemmaraju N, Jabbour E, Alvarado Y, Wierda W, Pinsoy MR, Ravandi F, Cortes JE